Pigmented progressive purpuric dermatosis
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References
Pigmented purpuric dermatoses (PPD) گروهی از بیماری های پوستی هستند که با قسمت های کوچک خونریزی زیر پوست به دلیل التهاب مویرگی مشخص می شوند. PPD معمولاً به صورت لکه‌های قرمز تا بنفش شروع می‌شود که بعداً با جذب مجدد هموسیدرین قهوه‌ای طلایی می‌شوند.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg disease رایج ترین نوع pigmented purpuric dermatoses (PPDs) است که بیماری های مزمن پوستی با لکه های قرمز یا بنفش کوچک و افزایش رنگ پوست (لکه های قهوه ای، قرمز یا زرد) مشخص می شود. PPD ها به پنج نوع طبقه بندی می شوند: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) با نام progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura نیز شناخته می شود. این عارضه عمدتاً مردان را مبتلا می‌کند و معمولاً در قسمت پایین ساق پا ظاهر می‌شود، اما می‌تواند روی ران‌ها، باسن، تنه یا بازوها نیز رخ دهد.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
اطلاعات 113 بیمار مبتلا به PPD، از جمله 38 بیمار که برای این مطالعه تحت بیوپسی پوست قرار گرفتند، تجزیه و تحلیل شد. شایع ترین نوع بالینی بیماری شامبرگ (60. 5%) بود. سایر شرایط در کنار PPD فشار خون بالا (15. 8٪) ، دیابت (10. 5٪) ، و دیگران بود. تاریخچه دارویی استاتین ها (13. 2٪) ، مسدود کننده های بتا (10. 5٪) و دیگران را نشان داد. عوامل احتمالی مرتبط با PPD شامل عفونت اخیر دستگاه تنفسی فوقانی (5. 3٪) ، ایستادن طولانی مدت که منجر به فشار ارتوستاتیک بالا (2. 6٪) و ورزش شدید (2. 6٪) می شود. درمان بر روی 36 بیمار (94. 7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy انجام شد.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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